Male Instructor standing in front of chalkboard answering Qsymia questions.

Qsymia®: 19 Frequently Asked Questions About This Weight Loss Medication

Dr. Matthew Olesiak
SANE MD Chief Medical Director at SANESolution

Introduction

If you’ve ever struggled with weight loss, you’re probably familiar with the frustrations that come with it. Qsymia®, a prescription medication, has been helping compatible individuals lose weight more effectively when combined with diet and exercise. But as with any medication, it’s normal to have questions. How does it work? What are the side effects? Is it right for you? In this article, we’ll dive into the ins and outs of Qsymia®, answering the most common questions to help you feel confident and informed.

Key Takeaways:

  • Combination Medication: Qsymia® contains phentermine and topiramate, working together to help reduce appetite and promote weight loss.
  • Who It’s For: It is typically recommended for a subset of adults who have a body mass index (BMI) of 30 kg/m2 or higher or for those with a BMI of 27 kg/m2 or higher who also have other weight-related health issues such as high blood pressure or diabetes.
  • Risks: While Qsymia® can lead to weight loss, it may also cause side effects such as increased heart rate, mood swings, and birth defects if used during pregnancy.

FAQs About Qsymia®

When you’re considering a new medication, it’s normal to feel a little overwhelmed by all the information. To make it easier, we’ve compiled a list of frequently asked questions about Qsymia®. These questions cover everything from how the drug works to potential side effects, giving you a clearer picture of what to expect. Whether you’re thinking of starting Qsymia® or just want to learn more, we’ve got you covered.

1. What exactly is Qsymia®, and how does phentermine topiramate work?

Qsymia® is a prescription drug that combines two active ingredients: phentermine and topiramate. Phentermine is an appetite suppressant, while topiramate helps with weight loss by affecting the brain’s hunger signals. When these two work together, they help reduce the urge to eat, making it easier to stick to a calorie-restricted diet. Paired with regular exercise, Qsymia® may help certain individuals achieve significant weight loss over time.

2. Who is Qsymia® meant for?

Doctors typically prescribe Qsymia® to a subset of adults struggling with obesity, which is defined as having a BMI of 30 or more. It’s also prescribed for individuals with a BMI of 27 or higher if they have weight-related medical problems such as high blood pressure, diabetes, or high cholesterol. The medication is most effective when combined with healthier lifestyle changes, like eating a balanced diet and increasing physical activity.

3. How effective is Qsymia® in helping with weight loss?

Qsymia® has shown to be effective for many people, with studies indicating an average weight loss of 5% to 10% of body weight over a year. Results can vary depending on factors like one’s Weight Loss Drug Type (quiz here) and how closely patients stick to their diet and exercise plans. It’s important to remember that Qsymia® works best when paired with those lifestyle changes, as it isn’t a magic pill on its own.

4. How quickly will I start to see results with Qsymia®?

Most people notice some weight loss within the first few weeks of starting Qsymia®, especially if they are also making healthy changes to their diet and exercise routines. However, it can take several months to see the full effects. If, after 12 weeks, you haven’t lost at least 3% of your body weight, your doctor might adjust the dosage or recommend stopping the medication.

5. What side effects should I be aware of when taking Qsymia®?

Like any medication, Qsymia® comes with potential side effects. The most common ones include dry mouth, constipation, and tingling sensations in your hands or feet. Some people might also experience dizziness or trouble sleeping. More serious side effects, such as increased heart rate or mood changes, are less common but should be discussed with your doctor.

Additionally, rare side effects like unusual tiredness or weakness and blood in the urine warrant immediate medical attention. Always stay in touch with your healthcare provider to monitor how you’re responding to the medication.

5 Most Common Qsymia Side Effects Infographic

6. Can I take Qsymia® if I’m pregnant, trying to become pregnant, or have a negative pregnancy test?

It’s strongly advised not to take Qsymia® if you’re pregnant or planning to become pregnant. The medication can cause serious birth defects, especially if taken in the early stages of pregnancy. Women who are of childbearing age must use effective birth control while on Qsymia® and have a negative pregnancy test before starting the medication.

7. How should I take Qsymia®?

Typically, Qsymia® is taken once a day, usually in the morning. Your doctor will start you on a low dose and gradually increase it based on your response to the medication and any side effects you might experience.

Be sure to follow your doctor’s instructions carefully, and don’t make any changes to your dosage without consulting them first.

8. Will Qsymia® have drug interactions with other medications I’m taking?

Qsymia® can have drug interactions with several other medications, such as antidepressants, seizure medications, or birth control pills. This is why it’s important to inform your healthcare provider about any medications or supplements you’re currently taking to manage these interactions effectively. They will be able to determine whether Qsymia® is safe for you or if adjustments need to be made to your treatment plan.

9. Is there anything I should avoid while taking Qsymia®?

While taking Qsymia®, it’s a good idea to avoid alcohol, as it can increase the likelihood of certain side effects, like dizziness or drowsiness. You should also be cautious when driving or operating machinery if you feel lightheaded or sleepy. Following your doctor’s guidance regarding lifestyle adjustments will help you avoid potential complications.

10. How long will I need to take Qsymia®?

How long you take Qsymia® depends on how well the medication works for you and your overall health plan. Some people take it for an extended period, while others may stop after a few months, depending on their progress. Regular check-ins with your doctor will help determine the best course of action for you.

11. What should I do if I miss a dose?

If you miss a dose of Qsymia®, take it as soon as you remember, unless it’s already close to your next scheduled dose. In that case, skip the missed dose and continue with your usual schedule. Never double up on doses to make up for a missed one, as this can increase your risk of side effects.

12. How much weight can I realistically expect to lose with Qsymia®?

The amount of weight loss varies from person to person, but most people can expect to lose between 5% and 10% of their initial body weight within a year. The key to success with Qsymia® is combining it with a healthy eating plan and regular physical activity to see the best results.

13. Is Qsymia® covered by insurance?

Whether or not your insurance covers Qsymia® depends on your provider and specific plan. Some insurance companies cover part of the cost, while others do not. It’s worth checking with your provider to see if Qsymia® is covered under your plan or if there are any assistance programs available to help with the cost.

14. Can I stop taking Qsymia® whenever I want?

It’s not recommended to abruptly stop taking Qsymia®. If you want to discontinue the medication, speak with your doctor first. They may suggest gradually reducing your dosage to avoid withdrawal symptoms or other issues. As always, follow your healthcare provider’s advice when making changes to your medication regimen.

15. What lifestyle changes should I make while on Qsymia®?

For the best results, make lifestyle changes that complement Qsymia®. Focus on eating a balanced, reduced-calorie diet and getting regular exercise. Staying hydrated, managing stress, and getting enough sleep will also help you achieve your weight loss goals more effectively.

16. What are the pros of using Qsymia®?

Qsymia® offers several benefits for compatible individuals looking to lose weight and improve their overall health. One of the primary advantages is its potential effect on body weight. Clinical trials have shown that Qsymia® can help individuals lose a significant amount of weight and maintain that loss over time. This can be particularly beneficial for those struggling with obesity-related health issues.

As a result of the weight loss, Qsymia® has been shown to help improve blood sugar control in certain individuals with type 2 diabetes, making it easier to manage this condition, reduce blood pressure in those with high blood pressure, contributing to better cardiovascular health, and improve lipid profiles by reducing triglycerides and increasing HDL (good) cholesterol levels.

Another advantage of Qsymia® is its convenience. The medication is available in extended-release capsules, which means it only needs to be taken once a day. This can help people adhere to their medication schedule and reach their weight loss targets more easily.

17. What are the cons of using Qsymia®?

While Qsymia® can be an effective tool for weight loss, it’s important to be aware of its potential drawbacks. One of the most common issues is the side effects, including dry mouth, constipation, and dizziness. These side effects can be bothersome and may affect your daily life.

Another significant concern is the increased risk of birth defects if Qsymia® is taken during pregnancy. This medication can cause serious birth defects, such as cleft lip and palate, so it’s crucial for women of childbearing age to use effective birth control and have a negative pregnancy test before starting Qsymia®.

Qsymia® can also interact with other medications, including birth control pills, potentially reducing their effectiveness. Additionally, it can cause metabolic acidosis, a condition where the body produces too much acid, which can lead to serious health issues if not monitored properly.

Lastly, Qsymia® can increase the risk of kidney stones. This is why it’s important to stay hydrated and follow your doctor’s recommendations to minimize this risk.

18. Are there alternatives to Qsymia® for weight loss?

Yes, there are several alternatives to Qsymia® for certain individuals seeking weight loss medications. One option is Orlistat (Alli, Xenical), which works by reducing the amount of fat absorbed by the body. This can help decrease calorie intake and promote weight loss.

Another alternative is Lorcaserin (Belviq), which helps reduce hunger and increase feelings of fullness, making it easier to stick to a reduced-calorie diet. Similarly, Bupropion-naltrexone (Contrave) and Liraglutide (Saxenda) work by reducing hunger and increasing satiety, aiding in weight loss efforts.

Phentermine-topiramate (Qsymia®) itself is a combination medication that helps reduce hunger and increase feelings of fullness. Still, other medications like those mentioned can be considered based on your Weight Loss Drug Type (quiz here), individual needs, and medical history. It’s important to discuss these options with your doctor to determine the best approach for your weight loss journey.

19. What monitoring and precautions should I consider while on Qsymia®?

When taking Qsymia®, it’s crucial to monitor for potential side effects and take necessary precautions to ensure your safety. Regular blood tests are important to check for any adverse effects, such as metabolic acidosis or kidney damage. These tests can help your doctor adjust your treatment plan as needed.

Women of childbearing age should have a negative pregnancy test before starting Qsymia® and use effective birth control while on the medication to prevent the risk of birth defects. Monitoring for signs of kidney stones, such as severe back or side pain, painful urination, and blood in the urine, is also essential.

Patients should be aware of the symptoms of metabolic acidosis, including nausea, vomiting, and rapid breathing, and report any such symptoms to their doctor immediately. It’s also important to avoid certain medications, such as prescription pain relievers, while taking Qsymia®, as they can interact negatively with the medication.

Avoiding a ketogenic diet is recommended, as it can increase the risk of kidney stones. Staying hydrated is crucial to minimizing this risk. Additionally, monitoring for any rash or stomach discomfort, as well as any unusual sense of well-being, is important to catch any adverse reactions early.

Lastly, patients should be aware of the potential for rare blood disorders and other serious side effects that may arise during clinical trials. Regular check-ins with your healthcare provider will help manage these risks and ensure the medication is working effectively for you.

Conclusion

Qsymia® can be a helpful tool in the weight loss journey for compatible individuals, but it’s most effective when paired with healthy lifestyle changes. It’s important to approach this medication with realistic expectations and stay in regular contact with your doctor. If you think Qsymia® might be right for you, take the Weight Loss Drug Type Quiz here and discuss your options with your healthcare provider.

References

https://qsymia.com/

https://www.medicine.com/drug/qsymia