How to Get a Zepbound Prescription: Online, Cost & Savings

Zepbound is a new FDA-approved weight loss medication designed to help individuals struggling with obesity and related health conditions. Manufactured by Eli Lilly, Zepbound contains tirzepatide as its active ingredient, a dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist that helps individuals lose weight and supports chronic weight management.

Zepbound for weight loss has gained attention for its effectiveness in promoting weight loss, as studies show Zepbound can result in a maximum of 20.9% loss in body weight when combined with diet and regular exercise. Additionally, Zepbound can help individuals lose 2-4 times more weight than diet and exercise alone. However, getting a Zepbound prescription can be confusing, especially when considering factors like online access, cost, insurance coverage, and savings options.

If you’re wondering how to get a Zepbound prescription: online, cost & savings, how much it costs with or without insurance, or whether coupons can lower your out-of-pocket expenses, this guide will provide clear, up-to-date answers. We’ll also cover who can prescribe Zepbound, alternative weight loss options, and ways to maximize your savings on this medication. Remember to take the Zepbound quiz to see if this weight loss medication is right for you.

Whether you’re starting your weight loss journey or looking for a cost-effective way to obtain Zepbound, this article will help you navigate the process confidently.

Key Takeaways

• Zepbound is available through online and in-person healthcare providers but requires a prescription from a licensed medical provider.
• Costs vary depending on insurance coverage, pharmacy, and available savings programs, with options for those without insurance.
• Coupons and manufacturer discounts can help lower the cost, making Zepbound a more affordable weight loss medication.

Can I Get Zepbound Online?

Zepbound prescriptions can be obtained online through licensed medical providers and telehealth services. Many online platforms connect patients with healthcare providers who can assess medical history and determine eligibility for a Zepbound prescription online.

According to Dr. Matthew Olesiak, Chief Medical Director of SANE MD, “Telemedicine has made it easier than ever for certain patients to access prescription weight loss medications like Zepbound, but it’s crucial to consult a qualified healthcare provider to ensure it’s the right treatment for you.”

Online Zepbound Prescription Options:

• Telehealth Services: Virtual consultations with licensed medical providers.
• Pharmacy Websites: Some partner with online doctors to offer Zepbound direct to consumer.
• Weight Loss Clinics: Some online weight loss programs offer access to Zepbound for weight loss if medically appropriate.

How to Get a Zepbound Prescription: Online, Cost & Savings

Method	Details
Online Prescription	Available through licensed telehealth providers and weight loss clinics. Services like WeightWatchers Clinic, Ro, and Sesame Care connect patients with providers who can assess eligibility and prescribe Zepbound.
Retail Cost	$1,059 – $1,300 per month without insurance. Price varies by pharmacy.
Insurance Coverage	Zepbound may be covered for eligible patients with BMI ≥30 or BMI ≥27 with a weight-related condition. Prior authorization is usually required.
Savings Programs	Eli Lilly offers manufacturer discounts (Lilly Savings Card, Patient Assistance Programs). Check eligibility through Lilly’s website.
Zepbound Coupons	Available through GoodRx, SingleCare, Blink Health, and local pharmacy discounts.
Best Price Strategies	Compare prices using GoodRx, ask about pharmacy membership discounts, and check LillyDirect for direct-to-consumer options.
Direct-to-Consumer (LillyDirect)	Eli Lilly offers home delivery for self-pay patients. Pricing may vary.
Compounded Tirzepatide	No longer available—the FDA has ended tirzepatide compounding due to the commercial availability of Zepbound from Eli Lilly.
Alternative Weight Loss Medications	Plenity (oral, non-systemic) vs. Zepbound (hormonal, injectable). Consult a healthcare provider to determine the best option.

How Can I Buy Zepbound Without Insurance?

Purchasing Zepbound without insurance coverage can be expensive. The retail price exceeds $1,000 per month.

However, several options can help reduce the cost and make Zepbound injections more affordable.

1. Manufacturer Savings Programs

Eli Lilly, the manufacturer of Zepbound, offers savings programs to eligible patients. These programs can provide significant discounts or rebates for individuals paying out-of-pocket. Single-use vials of Zepbound are only available from LillyDirect for cash-pay buyers who aren’t using insurance.

Some options include:

• Lilly Savings Card: May lower costs for those who qualify based on income and insurance status.
• Patient Assistance Programs (PAPs): Eli Lilly has financial assistance programs for individuals who meet specific income criteria.
• LillyDirect: Eli Lilly’s direct-to-consumer platform allows for more transparent pricing and may include discounts for self-pay patients. For Zepbound vials, additional supplies such as syringes and needles are needed for administration.

Zepbound vials are available as a ‘cash pay’ option through LillyDirect Pharmacy and are not eligible for insurance coverage. Zepbound 2.5 mg vials can be purchased starting at $349 per month.

To check eligibility, visit Lilly’s official website or ask your healthcare provider about manufacturer savings programs.

2. Zepbound Coupon Offers

Many pharmacies offer Zepbound coupons, which can significantly reduce the out-of-pocket price. Patients can access these through:

• GoodRx, WellRx, and SingleCare: These platforms provide pharmacy discount codes that may reduce the cost by hundreds of dollars.
• Local Pharmacies: Some independent and chain pharmacies may have in-store promotions or loyalty discounts.
• Pharmacy Membership Programs: Certain pharmacies offer savings clubs (e.g., Costco, Walmart, and Kroger), which can provide prescription discounts even without insurance plans.

3. Price Comparison Tools

Websites like GoodRx, Blink Health, and SingleCare allow patients to compare Zepbound prices at different pharmacies and find the best price in their area.

These platforms often display:

• Cash price vs. discount price comparisons
• Available Zepbound coupons and promo codes
• Pharmacies that offer Zepbound at a lower price

Using a price comparison tool before purchasing can help save hundreds of dollars per month on Zepbound.

4. Weight Loss Clinics & Online Services

Some weight loss clinics and telehealth services offer financing options or alternative ways to access Zepbound without insurance.

These may include:

• Telemedicine Providers: Online platforms like Sesame Care, Ro, and WeightWatchers Clinic connect patients with licensed medical providers who may prescribe Zepbound if medically appropriate.
• Financing & Payment Plans: Some clinics and pharmacies offer installment payment plans to make the cost more manageable.
• Weight Management Programs: Some clinics bundle consultations, nutrition guidance, and GLP-1 medications, making Zepbound slightly more affordable.

What About Compounded Tirzepatide?

During the initial launch of Zepbound, shortages led some patients to seek compounded tirzepatide from specialized pharmacies.

However, since the FDA has confirmed that the Zepbound shortage is over, compounding pharmacies will soon no longer be allowed to sell tirzepatide, an FDA-approved medication commercially available from Eli Lilly. Tirzepatide is the active ingredient in Zepbound, and patients should ensure they obtain Zepbound injections from a licensed pharmacy to guarantee safety and effectiveness.

How Much Is Zepbound With Weight Watchers?

As of this writing (March 7, 2025), WeightWatchers offers a GLP-1 Program designed to support members who use prescription weight loss medications, including Zepbound (tripeptide), Wegovy (semaglutide), and other GLP-1 receptor agonists.

While WeightWatchers does not directly prescribe Zepbound, its affiliated WeightWatchers Clinic (formerly Sequence) connects eligible members with licensed medical providers who can prescribe Zepbound if it aligns with their medical history and insurance coverage.

How the WeightWatchers GLP-1 Program Works

• Telehealth Consultations: Members complete an initial health assessment, and a licensed medical provider reviews their history.
• Prescription & Treatment Plan: If approved, the provider prescribes Zepbound injections and helps navigate insurance plans or self-pay options.
• Ongoing Support: Virtual dietitian support, lifestyle tracking, and GLP-1 community forums.
• Flexible Prescriptions: The program does not require members to obtain their Zepbound prescription through WeightWatchers; it also works with external providers.

Cost of Zepbound Through WeightWatchers (As of March 7, 2025)

• WeightWatchers GLP-1 Program Cost: Starts at $49 for the first month, then $74-$189 per month, depending on commitment length, plus a $49 consultation fee.
• Retail Cost of Zepbound: $1,059 per month without insurance coverage.
• Insurance & Savings: The WeightWatchers Clinic care team assists members in navigating prior authorization and potential savings programs.

Compounded Semaglutide & Future Tirzepatide Options

As of March 7, 2025, WeightWatchers offers compounded semaglutide (the active ingredient in Wegovy and Ozempic) for $129 for the first month, then $189 monthly.

Compounded tripeptide (Zepbound’s active ingredient) is not currently available, but given past shortages, WeightWatchers has structured its program to accommodate compounded medications if necessary.

Why WeightWatchers is Embracing GLP-1 Medications

Zepbound, FDA-approved in November 2023, has shown more significant weight loss results compared to single-hormone agonists like Wegovy. In clinical trials, patients lost up to 21% of body weight with Zepbound, compared to 15% with semaglutide (Wegovy). WeightWatchers integrates lifestyle strategies alongside these medications, emphasizing:

• Nutritional optimization (tracking protein, fruits/vegetables, water, and activity) to support muscle retention.
• Virtual workshops and a dedicated GLP-1 community to enhance long-term weight management.
• Post-medication transition plans to help patients maintain results after stopping Zepbound.

While some critics argue WeightWatchers’ GLP-1 strategy is a pivot from its traditional model, the company has embraced evidence-based obesity treatment to remain relevant in an evolving weight loss industry.

By leveraging Eli Lilly’s innovation while maintaining its behavioral health focus, WeightWatchers aims to support members beyond medication use.

How Much Does Zepbound Cost Without Insurance?

The cost of Zepbound without insurance varies by pharmacy, but most patients pay between $1,000 and $1,300 per month.

To lower costs, consider:

• Manufacturer savings programs
• Zepbound coupons
• Patient assistance programs
• Pharmacy discount cards

Zepbound 5 mg: Dosage and Cost

Zepbound 5 mg is a commonly prescribed maintenance dose for individuals undergoing chronic weight management. Zepbound is available in multiple dosage strengths, including 2.5 mg, 5 mg, 10 mg, 12.5 mg, and 15 mg, with 5 mg often used as a step-up dose after initial treatment with 2.5 mg. (Upon starting Zepbound, patients are usually prescribed 2.5 mg doses.) The site of Zepbound injection should be rotated weekly to minimize the risk of irritation or other injection site reactions.

The active ingredient, tripeptide, is a dual GIP and GLP-1 receptor agonist. It helps regulate appetite, slow gastric emptying, and improve metabolic function. After administration, the median time to maximum plasma concentration of Zepbound’s active ingredient is 24 hours.

Cost of Zepbound 5 mg

The cost of Zepbound 5 mg varies depending on insurance coverage, pharmacy pricing, and available savings programs. The retail price for a monthly supply without insurance can exceed $1,000 per month, but patients may be able to reduce this expense through:

• Insurance coverage and prior authorization approval
• Lilly’s Zepbound Savings Card for eligible patients
• Pharmacy discount programs and online prescription coupons

Patients prescribed Zepbound 5 mg should consult their healthcare provider about the best cost-saving options available for their specific insurance plan and pharmacy.

Zepbound Direct to Consumer: Is It Safe?

Yes, Zepbound direct-to-consumer services are available through licensed medical providers, telehealth platforms, and Eli Lilly’s direct-to-patient pharmacy service, LillyDirect.

These services allow eligible patients to obtain a Zepbound prescription online and have it delivered directly to their home.

Is Direct-to-Consumer Zepbound Safe?

When purchasing Zepbound through direct-to-consumer platforms, patients should ensure they are obtaining their medication from a reputable and licensed pharmacy.

Some key safety considerations include:

• Only obtaining prescriptions from board-certified healthcare providers
• Ensuring the pharmacy is licensed and compliant with U.S. regulations
• Verifying product authenticity to avoid counterfeit medications

Patients should be cautious of online platforms that do not require a prescription or offer suspiciously low prices. These may be fraudulent sources selling unsafe or counterfeit medications.

Zepbound Use ICD: Insurance and Billing Codes

Insurance companies often require a diagnosis code (ICD-10) for prior authorization of Zepbound. These codes help determine medical necessity for weight loss treatment and chronic weight management.

Common ICD-10 Codes for Zepbound:

• E66.01 – Morbid (severe) obesity due to excess calories
• E66.9 – Obesity, unspecified
• E66.3 – Overweight
• Z68.4X – Body Mass Index (BMI) of 40 or greater
• Z68.3X – Body Mass Index (BMI) of 30-39.9

Why ICD Codes Matter for Insurance Approval

Most insurance plans require prior authorization for Zepbound, which involves:

• Submitting a healthcare provider’s diagnosis and supporting medical records
• Providing proof of previous weight loss attempts (e.g., diet, exercise, other medications)
• Meeting specific BMI and comorbidity criteria

Patients should work with their healthcare provider and insurance company to ensure the correct ICD-10 codes are submitted for approval and potential insurance coverage of Zepbound.

Plenity Alternative: How Does It Compare?

Plenity is another weight loss medication that differs from Zepbound in both mechanism of action and effectiveness.

Unlike Zepbound, which is an injectable medication that influences metabolic hormones, Plenity is an oral, non-systemic treatment that works mechanically in the stomach.

Key Differences Between Zepbound and Plenity

• Zepbound (tirzepatide) is a receptor agonist that affects blood glucose levels, regulates appetite, and slows gastric emptying, which can lead to significant weight loss over time.
• Plenity is a hydrogel-based treatment that expands in the stomach after being taken with water. It creates a feeling of fullness to help reduce food intake. Unlike Zepbound, it does not affect hormones and is not absorbed into the bloodstream.

Which One Is Right for You?

While both medications aid in weight loss, their effectiveness varies:

• Zepbound has demonstrated superior weight loss results in clinical trials compared to many other medications, including GLP-1-only drugs like Wegovy.
• Plenity may be better suited for individuals seeking a non-hormonal, non-systemic approach or those who do not qualify for Zepbound injections.

Because these treatments function differently, patients should consult a healthcare provider to determine the best option for their weight goals, medical history, and insurance coverage.

Zepbound Coupon: How to Save Money

Many pharmacies and manufacturers offer Zepbound coupons and discount programs that can significantly lower the cost, especially for patients without insurance coverage.

How to Find Zepbound Discounts:

• Check Eli Lilly’s Official Website: The manufacturer often provides savings programs or rebate cards for eligible patients.
• Ask Your Local Pharmacy: Some retail pharmacies offer savings programs, discount cards, or promotional offers for cash-paying customers.
• Use Discount Services Like GoodRx, Blink Health, or SingleCare. These platforms help you compare pharmacy prices and provide instant coupons that can reduce your out-of-pocket cost.
• Look for Pharmacy Membership Programs: Some chains like Costco, Kroger, and Walmart offer prescription savings clubs that may include Zepbound discounts.

Taking advantage of these savings programs can substantially lower the cost of Zepbound, making it more accessible for patients on a weight loss journey.

Who Can Prescribe Zepbound?

Since Zepbound is a prescription medication, it can only be prescribed by a licensed medical provider. A healthcare professional will inform patients about the necessary lab work required before prescribing Zepbound.

This includes:

• Primary care doctors – General practitioners who assess a patient’s medical history and weight management needs.
• Endocrinologists – Specialists in hormonal and metabolic disorders, including obesity and diabetes.
• Obesity medicine specialists – Physicians trained in medical weight management who evaluate treatment options based on individual health goals.
• Telehealth providers – Online healthcare services that offer virtual consultations and, if appropriate, prescribe Zepbound for weight loss.

Considerations Before Getting a Zepbound Prescription:

Before prescribing Zepbound, healthcare providers will assess several factors, including:

• Medical history and current medications – To ensure Zepbound does not interact with other medications or pre-existing conditions.
• Potential risks – Some patients may not be eligible due to concerns such as thyroid tumors (medullary thyroid carcinoma risk) or gastrointestinal disorders.
• Injection site reactions and other adverse reactions – Zepbound is administered as a weekly injection, and some patients may experience mild to moderate side effects, such as nausea, vomiting, or injection site redness.

Patients should discuss their weight loss goals and medical conditions with their healthcare providers to determine whether Zepbound injections are the right option for them.

According to Dr. Matthew Olesiak, “A thorough evaluation of a patient’s medical history and health status is essential before prescribing any weight loss medication, including Zepbound.”

Frequently Asked Questions (FAQ) About Zepbound

Zepbound is a prescription weight loss medication developed by Eli Lilly. It is designed to help compatible individuals struggling with chronic weight management.

Whether you’re looking to obtain Zepbound injections, find cost-saving options, or understand how it compares to other GLP-1 medications, this FAQ section provides clear and accurate answers to the most common questions.

1. Can You Get a Zepbound Prescription Online?

You can obtain a Zepbound prescription online through licensed telehealth providers and weight loss clinics that offer virtual consultations.

Online platforms like WeightWatchers Clinic, Ro, and Sesame Care connect patients with licensed medical providers who assess medical history and determine whether Zepbound is appropriate.

However, patients should ensure they use reputable telemedicine services and obtain Zepbound injections from a licensed pharmacy to avoid counterfeit or unregulated medications.

2. How to Get Zepbound Injections?

To obtain Zepbound injections, follow these steps:

1. Consult a Healthcare Provider – Schedule an appointment with a primary care physician, endocrinologist, obesity medicine specialist, or telehealth provider.
2. Medical Evaluation – The provider will assess medical history, weight goals, and BMI to determine eligibility.
3. Prescription Approval – If approved, your provider will issue a Zepbound prescription.
4. Pharmacy Fulfillment: You can Pick up Zepbound injections at a local pharmacy, mail-order pharmacy, or direct-to-consumer service like LillyDirect.
5. Administer Weekly Injections – Zepbound is a once-weekly injectable that comes in a single-dose pen for self-administration.

If you are new to injectable medications, your doctor or pharmacist can provide guidance on proper injection site selection and administration.

3. What Is the Cheapest Way to Get Zepbound?

The cheapest way to get Zepbound depends on insurance coverage, savings programs, and pharmacy discounts.

Consider these cost-saving strategies:

• Use the Lilly Zepbound Savings Card – Eligible patients may qualify for significant discounts through Eli Lilly’s savings program.
• Check GoodRx and Other Discount Programs – Websites like GoodRx, Blink Health, and SingleCare offer pharmacy price comparisons and instant coupons.
• Verify Insurance Coverage – Some insurance plans cover Zepbound with prior authorization; check with your provider.
• Look for Pharmacy Promotions – Some retailers and online pharmacies offer temporary discounts or savings programs.

While Zepbound’s retail price exceeds $1,000 per month, eligible patients using manufacturer savings and insurance can substantially reduce costs.

4. Does Amazon Pharmacy Have Zepbound?

As of March 7, 2025, Amazon Pharmacy does not list Zepbound as an available medication. However, Amazon Pharmacy does carry other GLP-1 receptor agonists, such as Wegovy and Ozempic (semaglutide).

Patients interested in Zepbound injections should check Eli Lilly’s LillyDirect program, major retail pharmacies (CVS, Walgreens, Walmart, Costco), or telehealth platforms that offer direct fulfillment.

5. Do I Qualify for Zepbound?

To qualify for Zepbound, patients typically need to meet the following eligibility criteria:

• BMI of 30 or higher (classified as obese)
• BMI of 27 or higher with at least one weight-related condition (e.g., type 2 diabetes, high blood pressure, high cholesterol, obstructive sleep apnea)
• No history of medullary thyroid carcinoma (MTC) or multiple endocrine neoplasia syndrome type 2 (MEN2)
• No contraindications with existing medical conditions or medications

A licensed healthcare provider must assess your medical history and weight loss goals to determine whether Zepbound injections are a suitable treatment option.

6. Is Zepbound the Same as Mounjaro?

Zepbound and Mounjaro contain the same active ingredient, tirzepatide, but they are FDA-approved for different purposes:

• Mounjaro is FDA-approved for type 2 diabetes management.
• Zepbound is FDA-approved for chronic weight management in overweight and obese individuals.

Both medications function as GLP-1 and GIP receptor agonists, meaning they regulate appetite, slow gastric emptying, and improve metabolic function.

While their active ingredient is identical, the FDA-approved indications, branding, and insurance coverage differ.

Conclusion

Zepbound is a powerful FDA-approved weight loss medication. It requires a prescription from a licensed medical provider. Patients can obtain it online or in person, compare costs with and without insurance, and use coupons and savings programs to reduce expenses.

Consulting a healthcare provider is crucial to ensure safe and effective chronic weight management.