An image of a pair of bare feet on a bathroom scale.

Is Contrave Right for You? A Guide to Eligibility and Benefits

Dr. Matthew Olesiak
SANE MD Chief Medical Director at SANESolution

Dr. Matthew Olesiak, MD, is the Chief Medical Director at SANESolution, a renowned wellness technology company dedicated to providing evidence-based solutions for optimal living. Dr. Olesiak earned his medical degree from the prestigious Jagiellonian University Medical College in Kraków, Poland, where he developed a strong foundation in medicine.

Introduction

Contrave is a prescription weight loss medication that combines two active ingredients—bupropion and naltrexone—to support weight management by targeting appetite and cravings. Designed for adults struggling with obesity or weight-related health conditions, Contrave works as part of a broader approach involving diet and exercise.

Deciding whether Contrave is the right choice depends on individual eligibility, health history, and the potential benefits it may offer. Understanding these factors is essential for safe and effective weight loss. This article explores questions about what Contrave is, who it’s best suited for, and the advantages and considerations of using this medication.

Key Takeaways

  • Contrave combines bupropion and naltrexone to suppress appetite and manage cravings.
  • It is intended for adults with a BMI of 30+ or 27+ with weight-related health conditions.
  • Consulting with a healthcare provider is critical to determine eligibility and ensure safety.

What is Contrave? An Overview

Contrave is a prescription medication approved by the FDA in 2014 to assist with weight loss in adults who meet specific criteria. It contains two active components: bupropion, an antidepressant that also reduces appetite, and naltrexone, a drug used to treat addiction that may curb cravings. Together, these ingredients influence areas of the brain associated with hunger and reward, helping users achieve weight loss goals more effectively.

Unlike stimulant-based weight loss drugs, Contrave operates without affecting the central nervous system in the same way, making it a potential option for those who cannot tolerate stimulants. It is designed to be used alongside a reduced-calorie diet and increased physical activity to optimize results. Contrave’s dual-action approach differentiates it from other medications, offering an alternative for individuals struggling to control both appetite and cravings.

Eligibility Criteria for Contrave

BMI Requirements
Contrave is prescribed for adults with a body mass index (BMI) of 30 or higher, classifying them as obese. It is also an option for those with a BMI of 27 or higher if they have weight-related health conditions such as type 2 diabetes, high blood pressure, or high cholesterol. These criteria ensure the medication is targeted at individuals who may benefit most from its weight-loss properties.

Health Conditions
Candidates for Contrave often have weight-related health concerns that may improve with weight loss. Conditions such as insulin resistance, sleep apnea, and metabolic syndrome can make it difficult to lose weight without medical assistance. Contrave is part of a comprehensive plan to address these challenges.

Who Should Avoid Contrave
Certain individuals should not use Contrave due to safety concerns. It is contraindicated for:

  • Pregnant or breastfeeding individuals.
  • Those with seizure disorders or a history of seizures, as bupropion may increase seizure risk.
  • Individuals taking opioids, which can interact negatively with naltrexone.
  • People with uncontrolled hypertension or eating disorders such as bulimia or anorexia.

Consulting with a healthcare provider is essential to determine if Contrave is appropriate based on medical history, current medications, and overall health.

Benefits of Contrave

Weight Loss Support
Contrave targets two significant barriers to weight loss: appetite and cravings. By suppressing hunger signals and reducing the urge to overeat, it can help individuals adhere to a calorie-controlled diet. This dual action supports gradual, sustained weight loss when combined with lifestyle changes.

Health Improvements
Weight loss achieved with Contrave may contribute to improved health outcomes, such as lower blood pressure, better blood sugar control, and reduced cholesterol levels. These changes can decrease the risk of developing chronic diseases like heart disease or type 2 diabetes, providing long-term health benefits.

Quality of Life
Losing weight can also enhance quality of life by increasing energy levels, improving mobility, and boosting self-esteem. Many users report feeling more confident and capable of engaging in physical activities they previously avoided.

Best Results with Lifestyle Changes
Contrave works most effectively when paired with a healthy diet and regular physical activity. For example, incorporating nutrient-dense foods and consistent exercise can enhance weight loss outcomes while promoting overall wellness. This comprehensive approach ensures the medication complements, rather than replaces, a healthy lifestyle.

Risks and Considerations Before Choosing Contrave

Side Effects
Like all medications, Contrave comes with potential side effects. Common issues include nausea, headache, dizziness, constipation, and dry mouth, which often diminish as the body adjusts to the medication. More serious side effects, such as high blood pressure, seizures, or changes in mood, require immediate medical attention. Discussing potential side effects with a healthcare provider can help individuals prepare for what to expect.

Lifestyle Adjustments
Taking Contrave requires commitment to a healthier lifestyle. While the medication can help suppress appetite and control cravings, long-term success depends on adopting sustainable habits, such as eating a balanced diet and staying physically active. Consistency in these areas is key to achieving and maintaining weight loss.

Ongoing Monitoring
Regular check-ins with a healthcare provider are essential for monitoring progress and addressing any concerns. These appointments allow for adjustments to the treatment plan if necessary, ensuring the medication is used safely and effectively.

Financial Considerations
The cost of Contrave can be a barrier for some individuals. While insurance may cover the medication, coverage varies, and out-of-pocket expenses can be significant. Exploring discount programs or manufacturer coupons can help reduce costs. Consulting with a pharmacist or insurance provider can clarify coverage options.

Contrave: Risks and Considerations Infographic

Frequently Asked Questions About Contrave

  1. Who is the ideal candidate for Contrave?
    Contrave is recommended for adults with a BMI of 30 or higher or a BMI of 27 or higher with at least one weight-related condition, such as type 2 diabetes or hypertension. Candidates should be willing to commit to lifestyle changes like a healthy diet and regular exercise. A healthcare provider will evaluate individual medical histories and medications to determine if Contrave is a suitable option.
  2. Can Contrave be taken long-term?
    Contrave is intended for use over an extended period, provided it continues to support weight loss and the individual tolerates it well. Healthcare providers typically assess progress after 12 to 16 weeks to determine whether to continue treatment. If significant weight loss has not occurred, the provider may recommend discontinuing the medication.
  3. What lifestyle changes are necessary when taking Contrave?
    To achieve the best results, users should adopt a reduced-calorie diet and engage in regular physical activity. These changes help maximize weight loss and improve overall health. Additionally, individuals should focus on building sustainable habits, such as meal planning and incorporating movement into daily routines, to maintain progress after stopping the medication.
  4. Does Contrave work for everyone?
    While Contrave has been shown to aid weight loss for many users, it may not work for everyone. Factors such as adherence to lifestyle changes, individual metabolism, and response to the medication can affect outcomes. Regular consultations with a healthcare provider help determine whether Contrave is effective or if adjustments are needed.
  5. Is Contrave covered by insurance or discount programs?
    Insurance coverage for Contrave varies depending on the provider and individual plan. Many insurers require prior authorization or proof of medical necessity before covering the medication. For those without insurance coverage, manufacturer coupons and savings programs may lower the cost. Checking with a pharmacist or insurance representative can clarify available options.

Conclusion

Contrave offers a potential solution for adults struggling with weight management, particularly those who meet specific eligibility criteria and are committed to making lifestyle changes. Understanding its benefits, risks, and requirements ensures informed decision-making. Always consult a healthcare provider to determine if Contrave aligns with your health needs and goals. Sustainable weight loss relies not just on medication but also on a commitment to healthier habits.